There is no warranty of accuracy or completeness of any information contained herein. The byproduct of this distillation was subjected to an additional chlorination step and sold as aroclor 1254. Identification and quantitation of pcb aroclor mixtures in a single run using the agilent 7000b triple quadrupole gcms authors dale r. Pcb congener composition of aroclors a detailed analyses of the pcb congener distributions present in aroclors 1016, 1242, 1248, 1254, and 1260 note that the most abundant homologue groups are the di and trichlorinated biphenyls for the low chlorinated aroclors 1016 and 1242. Additionally, thyroid follicular cell adenomas or carcinomas were increased for all aroclors in male rats only. Supelco aroclor standard mix 1, aroclor standard 200 ugml dichloromethane 1x1ml, aroclor standard 200 ugml hexane 1x1ml. Half lives provide some indication of how fast a compound can volatilize from solution. For more details on the composition of differents aroclor mixtures, see. Your new online msds binder is a place for you to store the material safety data sheets you need to deploy. Aroclor 1242 standard safety data sheet according to regulation e c no.
Apf 50 any airpurifying, fullfacepiece respirator gas mask with a chinstyle, front or backmounted organic vapor canister having an n100, r100, or p100 filter. Aroclor 1242 is a pcb mixture that may increase e2 levels andor er binding jansen et al. Aroclor 1242 was a more potent inducer than aroclor 1016. The determination of polychlorinated biphenyls pcb using. Congenerbased analysis of the weathering of pcb aroclor. Aroclor 1254 aroclor 1260 aroclor 1242 aroclor 1016. At concentrations above the niosh rel, or where there is no rel, at any detectable concentration. Specific aroclors carried a fourdigit reference number e. Polychlorinated biphenyl aroclor 1242 toxicity data with reference. This table shows how each list refers to the substance.
Aroclor 1232 red 1242 green at first glance it appears that there are no differences with the exception of the peak heights. Measuring pcbs as aroclors relies on there being a relatively fixed composition of pcb congeners in the mixture. The information in cameo chemicals comes from a variety of data sources. Recently, as i was digesting data and researching literature to prepare for my umass soils conference presentation this fall, i discovered something interesting about aroclor 1254 that i hadnt known. The halflives for aroclor 1242, aroclor 1248, aroclor 1254, and aroclor 1260 are reported to be 12. Note that the progression of weathering resulted in altering aroclor 1242 to resemble standard aroclor 1248. The identity of the 209 pcb congeners is shown in table 42. Complete characterization of polychlorinated biphenyl congeners in commercial aroclor and clophen mixtures by multidimensional gas chromatographyelectron capture detection detlef e. Table of aroclors casrn iupac name type 12674112 aroclor 1016 mixture 147601874 aroclor 1210 mixture 151820278 aroclor 1216 mixture 11104282 aroclor 1221 mixture 37234405 aroclor 1231 mixture 11141165 aroclor 1232 mixture 728897 aroclor 1240 mixture 53469219 aroclor 1242 mixture. Polychlorinated biphenyl aroclor 1242 supplier casno. Aroclor 1242 had approximately 150 ppb of chlorinated dibenfurans, of which 43% was the toxic 2,3,7,9tetrachloro isomer. Pdf complete pcb congener distributions for 17 aroclor mixtures.
For more information about the substance, you may click one of the links below to take you to the relevant section. Aroclor 1254 exposure data were not available atsdr 1995. Program and regulatory information about this substance, including links to epa applicationssystems, statuesregulations, or other sources that track or regulate this substance. Aroclor definition of aroclor by the free dictionary.
Anaerobic dechlorination of aroclor 1242 as affected by some environmental conditions. In addition to being registered as an iso 9001 facility, spex certiprep is accredited by a2la as complying with the requirements of isoiec 17025 and iso 17034. The chemical identity of the aroclors is summarized in table 41. A comparison was made of the induction responses of two pcbs aroclors 1016 and 1242 on the hepatic microsomal mixed function oxidase mfo system in two genetically similar species, mink and european ferrets, previously shown to differ significantly in sensitivity to these same aroclors. Tables 3 and 4 summarize the compositions of common. Aroclor 1254 is a widely studied commercial polychlorinated biphenyl pcb mixture which, by definition, contains 54% chlorine by weight. Using a dosing regime which resulted in toxic effects in mink but not in ferrets, greater induction was noted in ferrets compared to mink. Gcecd chromatogram of pcb mixture aroclor 1242, 1254, and.
An aroclor pcb mixture might consist of over 100 different individual pcb congeners, although 10 to 20 congeners might make up over 50 percent of the mixture. Polychlorinated biphenyl aroclor 1242 analytical methods for occupational chemical analysis use niosh. The complete polychlorinated biphenyl compositions of two american products, aroclor 1242 and its more modern replacement, aroclor 1016, have been determined by gasliquid chromatography glc on twelve liquid phases of differing selectivities. However, around 1971 the formula for making aroclor 1254 changed in a fundamental way giving rise to what is now referred to as type 2 aroclor 1254. Pcbs were manufactured and sold as complex mixture s of several congeners with a variety of trade names, including aroclor e. Example of documented pcb dechlorination processes and pathways, including pathways resulting in an increase in pcb19 and pcb4. Thus, aroclor 1242 is a chlorinated biphenyl mixture of varying amounts of. Aroclor 1016 was a refined version of aroclor 1242 that contained a lower percentage of higher and lower chlorinated congeners.
Aug 01, 2014 aroclor 1260 production represented approximately 10. Santa clara, ca 95636 application note abstract a unique method has been developed to enable identification and quantitation of. Pcb congener composition of aroclors 1248 top and 1260 bottom19 figure 23. Sections i health hazard assessments for noncarcinogenic effects and. To view more metadata about the specific synonym, click on the synonym. The aroclor 1242 diets caused complete reproductive failure at levels as low as five ppm of the diet.
Anaerobic dechlorination of aroclor 1242 as affected by. See working with the information on this page section below for important notes about this data. Apf 10,000 any selfcontained breathing apparatus that has a full facepiece and is operated in a pressuredemand or other positivepressure mode. From 1957 to 1971, the 20 million kilograms of aroclor 1242 that were used in carbonless copy paper represented 6. Nioshtic2 publications search 00080820 failure report. Aroclor 1242 toxicity, ecological toxicity and regulatory. Sep 06, 2011 while each batch of pcbs differed slightly in its exact chemical composition based on the percentages of the the individual pcb congeners present, these differences from batch to batch were small. Aroclor 1242 solution, certified reference material, 500 mgkg in transformer oil, 48706 aroclor 1242 solution, certified reference material, 200. It is composed of mono to heptachlorinated homologs.
Aroclor synonyms, aroclor pronunciation, aroclor translation, english dictionary definition of aroclor. In mink, aroclor 1242 was found to be more toxic than comparable or higher levels of aroclor 1016. H410 very toxic to aquatic life with long lasting effects. Interestingly, these investigators observed a decrease in mammary tumors in female rats exposed to aroclor 1260, 1254, and 1242. Aroclor 1242 was the main mixture used in the 1950s and 1960s until it was. The transformer oil containing commercial pcb mixtures aroclor 1242, 1254 and. Less chlorinated pcbs were quantitated as aroclor 1242, and more highly.
Comparison of the compositions of aroclor 1242 and aroclor. Aroclor 1242 high level pcb1242h organic standards. The composition of commercial clophen a60 and phenoclor dp6 is similar to aroclor 1260. For additional information on the health effects of this. Aroclor 1260 production represented approximately 10. Epa rfdrfc work group and determined to be inadequate for the derivation of an oral rfd. In electrical equipment manufacturing in the us, aroclor 1260 and aroclor 1254 were the main mixtures used before 1950. Use water spray or fog for cooling exposed containers. Diets that contained various levels of supplemental aroclor 1242 or aroclor 1016 were fed to mink and ferrets to investigate the chronic toxicity of these pcbs in two closely related species. Identification and quantitation of pcb aroclor mixtures in a. Nonetheless, aroclor 1260 was selected for this study because of the resemblance in congener composition pattern to that of human fat mcfarland and.
Recent reports indicate substantial differences in the congener composition among aroclor lots and hence their biologic effects. Excerpt from erg guide 171 substances low to moderate hazard. Aroclor 1254 was used at first, but usage was later changed to aroclor 1242 and then to aroclor 1016. Other companies are charging thousands of dollars to set up accounts and give you access to their msds online database. Aroclor 1242 identification, toxicity, use, water pollution potential, ecological toxicity and regulatory information note. The workers had been employed at least 3 months between 1940 and 1976. Hepatocellular carcinoma was the most frequently found lesion in animals sacrificed at the end of the experiment, observed in 2, 3, and 61% of the animals in the control, clophen a30 and clophen. Halflives will be longer when depths are greater than 1 m. A handbook for determining the sources of pcb contamination. Pcb data set 1 is provided in the supplementary material on this books. Shop target for notebooks you will love at great low prices. Aroclor 1254 is one of several commercial pcb mixtures that were marketed between the 1930s and 70s. Table 44, and the congener composition of aroclors is shown in table 45.
Production, importexport, use, and disposal chemical company produced aroclors 1221, 1232, 1242, 1248, 1254, 1260, 1262, and 1268. Subsequent testing showed aroclor 1254 produced by this new process contained higher amounts of coplanar pcbs and pcdfs than the original formulation. Aroclor 1242 solution certified reference material. Aroclor 1242 was the main mixture used in the 1950s and 1960s until it was phased out in 1971 and replaced by aroclor 1016. Identification of the substancemixture and of the companyundertaking. The new aroclor 1016 was made by distilling aroclor 1242. Comparison of composition of aroclor mixtures tested. Feeding aroclors for 28 days at a subtoxic level 20 ppm resulted in weak induction of the. The complete polychlorinated biphenyl compositions of two american products, aroclor 1242 and its more modern replacement, aroclor 1016, have been determined by gasliquid chromatograhy glc on twelve liquid phases of differing selectivities.
The oral reference dose rfd is based on the assumption that thresholds exist for certain toxic effects such as cellular necrosis. The determination of polychlorinated biphenyls pcb using epa method 8082. Statutesregulations synonym synonym quality effective date end date. Thus, mcs 1016 was the designation of the aroclor 1242. Santa clara, ca 95636 application note abstract a unique method has been developed to. The exception to the naming system is aroclor 1016 which was produced by distilling 1242 to remove the highly chlorinated congeners to make a more biodegradable product. Aroclor 1242 was used as a solvent encapsulated with dye into microspheres and applied to one side of the paper during the. This light yellow viscous liquid is a particularly highly chlorinated pcb mixture which, by definition, contains 54% chlorine by weight. Aroclor 1248 is a commercial mixture of pcbs with an average chlorine content of 48%. Clophen a60 is almost identical in composition to aroclor 1260 iarc 1978, while clophen a30 appears to be similar in structure to aroclor 1016.
Comparison of the compositions of aroclor 1242 and aroclor 1016. The paper describes a novel type of anisotropic phantoms designed for b. Anaerobic dechlorination of aroclor 1242 as affected by some. H372 causes damage to organs through prolonged or repeated exposure. Both the in vitro and in vivo findings support the novel concept of chlorpyrifos as. Feeding aroclors for 28 days at a subtoxic level 20 ppm resulted in weak induction of the mfo system. Als environmental does not sell chemicals, but offers analytical lab testing to determine the presence of various elements and chemical compounds. A polychlorinated biphenyl pcb is an organic chlorine compound with the formula. Percen t composition allows us to see ar oclor fingerprint in the e nvironmental and biol ogical samples. Zodiac, a novel by neal stephenson which involves pcbs and their impact.
As an immediate precautionary measure, isolate spill or leak area in all directions for at least 50 meters 150 feet for liquids and at least 25 meters 75 feet for solids. Information on toxicological effects acute toxicity. Not classified aroclor 1242 5 3469219 ld50 oral rat 4250 mgkg r at ate clp o ral 4250. The hazard fields include special hazard alerts air and water reactions, fire hazards, health hazards, a reactivity profile, and details about reactive groups assignments and potentially incompatible absorbents. Walker and fred feyerherm agilent technologies, inc. Structure, properties, spectra, suppliers and links for. Information provided on aroclor 1242 53469219 is for reference only and is subject to change. The verification status for this chemical currently is not verifiable. Epa region 4 technical services section issue paper for.
S120 for the detection and assay of chlorodiphenyl 42% chlorine aroclor 1242 53469219 was tested and found to be unacceptable. Polychlorinated biphenyls world health organization. Table of aroclors casrn iupac name type 12674112 aroclor 1016 mixture 147601874 aroclor 1210 mixture 151820278 aroclor 1216 mixture 11104282 aroclor 1221 mixture 37234405 aroclor 1231 mixture 11141165 aroclor 1232 mixture 728897 aroclor 1240 mixture 53469219 aroclor 1242. Development of advisory levels for polychlorinated. Polychlorinated biphenyls pcbs are a group of 209 synthetic organic compounds with 110 chlorine atoms attached to biphenyl. Substance name aroclor 1016 casrn 12674112 last revised 01011993.
Please post your buying leads,so that our qualified suppliers will soon contact you. Chemidplus 53469219 aroclor 1242 similar structures. Complete characterization of polychlorinated biphenyl. Identification and quantitation of pcb aroclor mixtures in. Indole3carbinola novel approach to breast cancer prevention.
Wadsworth center for laboratories and research, albany, new york 12201. Dec 19, 2011 there were nine common pcb aroclor mixtures 1221, 1232, 1242, 1016, 1248, 1254, 1260, 1262, and 1268, and each of them has a distinctive gas chromatographic pattern. Feb 01, 1979 comparison of the compositions of aroclor 1242 and aroclor 1016. Aroclor 1254 has been extensively used and dispersed from industrial applications worldwide and its effects have been widely studied. Sigmaaldrich offers a number of aroclor 1242 solution products. Their composition was previously analyzed by frame, cochran, and bowadt 1996. Polychlorinated biphenyls pcb are considered persistent organic pollutants.